
朱泉霏,博士,教授。
一、個人簡介
2017年于武漢大學化學與分子科學學院獲得博士學位(分析化學專業);2018年至2021年在武漢大學和澳門科技大學開展博士後研究;2022年至2023年在武漢大學公共衛生學院 特聘副研究員;2024年起77779193永利官网教授。 主要研究方向為基于化學衍生化的色譜質譜代謝物分析方法研究,主要緻力于基于質譜的代謝組學分析方法研究,針對低豐度代謝物定性定量困難、代謝組學研究覆蓋度低等問題,通過發展高效的化學衍生化輔助的液相色譜-質譜分析技術,構建基于化學标記的代謝物數據庫,建立高靈敏的靶向代謝組、精細亞代謝組和非靶向代謝組分析研究平台,深度篩查和定量分析生物樣品中代謝組,發現和鑒定功能性代謝物。同時,緻力于利用所開發的方法,針對公共衛生/環境健康的科學問題開展合作研究。近年來在Analytical Chemistry, Trends in Analytical Chemistry等期刊上發表SCI論文50餘篇,其中以第一作者或共同通訊作者身份發表SCI論文23篇。作為負責人主持國家自然科學基金青年項目1項,中國博士後科研基金1項和“澳門青年學者計劃”資助1項,參與國家自然科學基金委重點項目、國際(地區)合作與交流項目以及國家科技部“973”課題等多項科研項目,入選武漢市人才計劃(武漢英才優秀青年)。現為《色譜》青年編委、J. Anal. Test青年編委,湖北省生物信息學會—微生物信息學專委會委員。
二、研究領域
1. 基于衍生化技術的色譜-質譜分析方法及其應用研究;
2. 代謝組學;
三、部分代表性論文
1. Na An, Yu Wang, Dong-Xiao He, Peng-Cheng Mei, Quan-Fei Zhu*, Yu-Qi Feng*, A dataset of branched fatty acid esters of hydroxy fatty acids diversity in foods, Scientific Data, 2023, 10: 790.
2. Jun-Di Hao, Yao-Yu Chen, Yan-Zhen Wang, Na An, Pei-Rong Bai, Quan-Fei Zhu*, Yu-Qi Feng*, Novel Peak Shift Correction Method Based on the Retention Index for Peak Alignment in Untargeted Metabolomics, Analytical Chemistry, 2023, 95, 13330-13337.
3. Yan-Zhen Wang, Yao-Yu Chen, Xin-Ze Wu, Pei-Rong Bai, Na An, Xia-Lei Liu, Quan-Fei Zhu*, Yu-Qi Feng*, Uncovering the Carboxylated Metabolome in Gut Microbiota-Host Co-metabolism: A Chemical Derivatization-Molecular Networking Approach. Analytical Chemistry, 2023, 95, 11550-11557.
4. Yu-Ning Hu, Jin-Tao Zhan, Pei-Rong Bai, Na An, Jun-Jie Tan, Yan-Zhen Wang, Quan-Fei Zhu*, Yu-Qi Feng*, In-depth profiling of di(2-ethylhexyl) phthalate metabolic footprints in rats using click chemistry-mass spectrometry probes. Journal of Hazardous Materials, 2023, 452, 131190.
5. Quan-Fei Zhu, Yan-Zhen Wang, Na An, Jun-Di Hao, Peng-Cheng Mei, Ya-Li Bai, Yu-Ning Hu, Pei-Rong Bai, Yu-Qi Feng*, Alternating Dual-Collision Energy Scanning Mass Spectrometry Approach: Discovery of Novel Microbial Bile-Acid Conjugates. Analytical Chemistry, 2022, 94, 2655-2664.
6. Na An, Quan-Fei Zhu*, Yan-Zhen Wang, Cai- Feng Xiong, Yu-Ning Hu, Yu-Qi Feng*, Integration of chemical derivatization and in-source fragmentation mass spectrometry for high-coverage profiling of submetabolomes. Analytical Chemistry, 2021, 93, 11321-11328.
7. Quan-Fei Zhu, Na An, Yu-Qi Feng*, In-Depth Annotation Strategy of Saturated Hydroxy Fatty Acids Based on Their Chromatographic Retention Behaviors and MS Fragmentation Patterns. Analytical Chemistry, 2020, 92, 14528-14535.
8. Quan-Fei Zhu, Tian-Yi Zhang, Lin-Lin Qin, Xin-Ming Li, Shu-Jian Zheng, and Yu-Qi Feng*, Method to Calculate the Retention Index in Hydrophilic Interaction Liquid Chromatography Using Normal Fatty Acid Derivatives as Calibrants, Analytical Chemistry, 2019, 91: 6057-6063.
9. Tian-Yi Zhang, Sha Li, Quan-Fei Zhu*, Qing Wang, Dilshad Hussain ,Yu-Qi Feng*, Derivatization for liquid chromatography-electrospray ionization-mass spectrometry analysis of small-molecular weight compounds, TrAC-Trends in Analytical Chemistry, 2019, 119, 115608.
10. Quan-Fei Zhu, Jing-Wen Yan, Tian-Yi Zhang, Hua-Ming Xiao, and Yu-Qi Feng*, Comprehensive screening and identification of fatty acid esters of hydroxy fatty acids in plant tissues by chemical isotope labeling-assisted liquid chromatography-mass spectrometry, Analytical Chemistry, 2018, 90: 10056-10063.